MolNFT v1 · #178625 · protein
Crystal structure of BCL-xl in complex with compound 1620116, crystal form 2
7JGV: “Crystal structure of BCL-xl in complex with compound 1620116, crystal form 2”. X-ray diffraction, 1 ligand (V9S). MolNFT v1 #178625 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7JGV
- Type
- protein
- Length
- 281 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q07817
- Ligands
- V9S
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 140 | — | Q07817 |
| B | — | protein | 141 | — | Q07817 |
Ligands and binding sites
- V9S · 6-[(8E)-8-{2-[4-(benzylcarbamoyl)-1,3-thiazol-2-yl]hydrazinylidene}-5,6,7,8-tetrahydronaphthalen-2-yl]-3-(2-phenylethoxy)pyridine-2-carboxylic acid · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7JGV · Crystal structure of BCL-xl in complex with compound 1620116, crystal form 2 · the same entry in another collection · chain A against A, TM-score 1.00
- Q07817 · AlphaFold monomer V2.0 prediction for BCL-2-like protein 1 (Q07817) · a predicted model of the same protein · chain B against A, TM-score 0.74
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q07817
- Elsewhere: RCSB PDB 7JGV · PDBe 7JGV · UniProt Q07817
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