MolNFT v1 · #178613 · protein
Cryo-EM structure of P. falciparum VAR2CSA NF45 DBL5 and DBL6 domains at 4.88 a
7JGG · Erythrocyte membrane protein 1: “Cryo-EM structure of P. falciparum VAR2CSA NF45 DBL5 and DBL6 domains at 4.88 a”. Electron microscopy, 9 pockets (best druggability 0.84). MolNFT v1 #178613 on GenesisL1: 3D structure, binding sites…
- PDB
- 7JGG
- Type
- protein
- Length
- 506 residues
- Chains
- 1
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Erythrocyte membrane protein 1
- UniProt
- W7K270
- Pockets
- 9 · best druggability 0.84
Structure
electron microscopy · 1 distinct chain · 62% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Erythrocyte membrane protein 1 | protein | 506 | 62% helix, 0% strand | W7K270 |
Pockets
9 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1007 | 0.84 | 0.85 | 111 | empty |
| 2 | 473 | 0.82 | 0.88 | 53 | empty |
| 3 | 400 | 0.72 | 0.83 | 45 | empty |
| 4 | 458 | 0.69 | 0.79 | 34 | empty |
| 5 | 233 | 0.60 | 0.80 | 31 | empty |
Modifications
Observed in the structure: 5 disulfide (disulfide).
Compared structures
- 7JGG · Cryo-EM structure of P. falciparum VAR2CSA NF45 DBL5 and DBL6 domains at 4.88 A · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt W7K270
- Elsewhere: RCSB PDB 7JGG · PDBe 7JGG · UniProt W7K270
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.