MolNFT v1 · #178599 · protein

Secretory immunoglobin a (siga)

7JG2: “Secretory immunoglobin a (siga)”. Electron microscopy, 3 ligands (NAG, BMA, MAN). MolNFT v1 #178599 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7JG2
Type: protein
Length: 1,584 residues
Chains: 6
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: Q99M22, O70570, P01592
Ligands: NAG, BMA, MAN

Structure

electron microscopy · 4 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, C, D	—	protein	231	—	Q99M22
B	—	protein	224	—	Q99M22
E	—	protein	535	—	O70570
J	—	protein	132	—	P01592

Ligands and binding sites

NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 12 copies · chains E, J, A, C, D
BMA · beta-D-mannopyranose · sugar · 2 copies
MAN · alpha-D-mannopyranose · sugar · 2 copies

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7JG2 · Secretory Immunoglobin A (SIgA) · the same entry in another collection · chain J against J, TM-score 1.00
P01592 · AlphaFold monomer V2.0 prediction for immunoglobulin J chain (P01592) · a predicted model of the same protein · chain J against A, TM-score 0.94
O70570 · AlphaFold monomer V2.0 prediction for polymeric immunoglobulin receptor (O70570) · a predicted model of the same protein · chain E against A, TM-score 0.94

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q99M22
Every structure of UniProt O70570
Every structure of UniProt P01592
Elsewhere: RCSB PDB 7JG2 · PDBe 7JG2 · UniProt Q99M22 · UniProt O70570 · UniProt P01592

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