MolNFT v1 · #178555 · protein

Ribonuclease T1/2',3'-cgps, non-productive

7GSP: “Ribonuclease T1/2',3'-cgps, non-productive”. X-ray diffraction, 2 ligands (SGP, PO4), 1 pocket (best druggability 0.48). MolNFT v1 #178555 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7GSP
Type: protein
Length: 208 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ribonuclease T1
EC: 3.1.27.3
UniProt: P00651
Ligands: SGP, PO4
Pockets: 1 · best druggability 0.48

Structure

x-ray diffraction · 1 distinct chain · 16% helix, 31% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Ribonuclease T1 (EC 3.1.27.3)	protein	104	16% helix, 31% strand	P00651

Ligands and binding sites

SGP · Guanosine-2',3'-cyclophosphorothioate · ligand · 2 copies · chains A, B
PO4 · Phosphate ion · ion · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	149	0.48	0.78	34	empty

Interfaces

1 interface between chains.

A–B · 308 Å² buried · 4 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 4 disulfide (disulfide).

Compared structures

7GSP · Ribonuclease T1/2',3'-cgps, non-productive · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P00651
Elsewhere: RCSB PDB 7GSP · PDBe 7GSP · UniProt P00651

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.