MolNFT v1 · #178423 · protein

Human serum ALBUMIN_2

7FFR: “Human serum ALBUMIN_2”. X-ray diffraction, 8 pockets (best druggability 0.84). MolNFT v1 #178423 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7FFR
Type: protein
Length: 571 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Serum albumin
UniProt: P02768
Pockets: 8 · best druggability 0.84

Structure

x-ray diffraction · 1 distinct chain · 70% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Serum albumin	protein	571	70% helix, 0% strand	P02768

Pockets

8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1017	0.84	0.85	112	empty
2	79	0.65	0.91	21	empty
3	147	0.56	0.81	20	empty
4	110	0.48	0.80	19	empty
5	101	0.46	0.79	18	empty

Modifications

Observed in the structure: 17 disulfide (disulfide).

Compared structures

7FFR · Human Serum Albumin_2 · the same entry in another collection · chain A against A, TM-score 1.00
P02768 · AlphaFold monomer V2.0 prediction for albumin (P02768) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P02768
Elsewhere: RCSB PDB 7FFR · PDBe 7FFR · UniProt P02768

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