MolNFT v1 · #178272 · protein

CARM1 bound with compound 9

7FAI: “CARM1 bound with compound 9”. X-ray diffraction, 1 ligand (XJ3). MolNFT v1 #178272 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7FAI
Type: protein
Length: 1,339 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: Q86X55
Ligands: XJ3

Structure

x-ray diffraction · 3 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	333	—	Q86X55
B	—	protein	334	—	Q86X55
C, D	—	protein	336	—	Q86X55

Ligands and binding sites

XJ3 · N'-[[3-[4-(3,5-dimethyl-1,2-oxazol-4-yl)-5-methyl-6-(oxan-4-ylamino)pyrimidin-2-yl]phenyl]methyl]-N-methyl-ethane-1,2-diamine · ligand · 4 copies · chains A, B, C, D

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7FAI · CARM1 bound with compound 9 · the same entry in another collection · chain D against D, TM-score 1.00
Q86X55 · AlphaFold monomer V2.0 prediction for histone-arginine methyltransferase CARM1 (Q86X55) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q86X55
Elsewhere: RCSB PDB 7FAI · PDBe 7FAI · UniProt Q86X55

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