MolNFT v1 · #178255 · protein
Toxoplasma gondii prolyl-tRNA synthetase (tgprs) in complex with inhibitor L95, L-proline and febrifugine
7F9R: “Toxoplasma gondii prolyl-tRNA synthetase (tgprs) in complex with inhibitor L95, L-proline and febrifugine”. X-ray diffraction, 3 ligands (JE6, 9SF, CL). MolNFT v1 #178255 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7F9R
- Type
- protein
- Length
- 487 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- A0A7J6JUK2
- Ligands
- JE6, 9SF, CL
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 487 | — | A0A7J6JUK2 |
Ligands and binding sites
- JE6 · ~{N}-[4-[(3~{S})-3-cyano-3-cyclopropyl-2-oxidanylidene-pyrrolidin-1-yl]-6-methyl-pyridin-2-yl]-2-phenyl-ethanamide · ligand · chains A
- 9SF · 3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one · ligand · chains A
- CL · Chloride ion · ion · 2 copies · chains A
- EDO · 1,2-ethanediol · additive · 7 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7F9R · Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in Complex with inhibitor L95, L-Proline… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A7J6JUK2
- Elsewhere: RCSB PDB 7F9R · PDBe 7F9R · UniProt A0A7J6JUK2
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