MolNFT v1 · #178229 · protein
Crystal structure of the mycobacterium tuberculosis L,D- transpeptidase-2 (LDTMT2) with new carbapenem drug T203
7F8P: “Crystal structure of the mycobacterium tuberculosis L,D- transpeptidase-2 (LDTMT2) with new carbapenem drug…”. X-ray diffraction, 2 ligands (59I, 56X). MolNFT v1 #178229 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7F8P
- Type
- protein
- Length
- 702 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- I6Y9J2
- Ligands
- 59I, 56X
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 352 | — | I6Y9J2 |
| B | — | protein | 350 | — | I6Y9J2 |
Ligands and binding sites
- 59I · (2R,3R)-3-methyl-4-(2-oxidanylidene-2-propan-2-yloxy-ethyl)sulfanyl-2-[(2R)-3-oxidanyl-1-oxidanylidene-butan-2-yl]-2,3-dihydro-1H-pyrrole-5-carboxylic acid · ligand · chains A
- 56X · (4R,5S,6S)-6-((R)-1-hydroxyethyl)-3-((2-isopropoxy-2-oxoethyl)thio)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid · ligand · chains A
- GOL · Glycerol · additive · 3 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- I6Y9J2 · AlphaFold monomer V2.0 prediction for L,D-transpeptidase 2 (I6Y9J2) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt I6Y9J2
- Elsewhere: RCSB PDB 7F8P · PDBe 7F8P · UniProt I6Y9J2
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