MolNFT v1 · #178211 · protein

Crystal structure of CRISPR-associated CAS2C of leptospira interrogans

7F84 · CRISPR-associated endoribonuclease CAS2: “Crystal structure of CRISPR-associated CAS2C of leptospira interrogans”. X-ray diffraction, 1 pocket (best druggability 0.55). MolNFT v1 #178211 on GenesisL1: 3D structure, binding sites and…

PDB: 7F84
Type: protein
Length: 178 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: CRISPR-associated endoribonuclease CAS2
EC: 3.1.-.-
UniProt: Q72NB8
Pockets: 1 · best druggability 0.55

Structure

x-ray diffraction · 1 distinct chain · 36% helix, 38% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	CRISPR-associated endoribonuclease CAS2 (EC 3.1.-.-)	protein	89	36% helix, 38% strand	Q72NB8

Ligands and binding sites

GOL · Glycerol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	189	0.55	0.79	26	empty

Interfaces

1 interface between chains.

A–B · 1704 Å² buried · 43 hydrogen bonds · protein-protein

Compared structures

7F84 · Crystal structure of CRISPR-associated Cas2c of Leptospira interrogans · the same entry in another collection · chain B against B, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q72NB8
Elsewhere: RCSB PDB 7F84 · PDBe 7F84 · UniProt Q72NB8

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