MolNFT v1 · #177971 · protein
Phosphodiesterase-9A in complex with inhibitor 4B
7F0I: “Phosphodiesterase-9A in complex with inhibitor 4B”. X-ray diffraction, 3 ligands (06A, ZN, MG). MolNFT v1 #177971 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7F0I
- Type
- protein
- Length
- 630 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Ligands
- 06A, ZN, MG
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 316 | — | — |
| B | — | protein | 314 | — | — |
Ligands and binding sites
- 06A · 1-cyclopentyl-6-[[(2R)-1-(6-fluoranyl-2-azaspiro[3.3]heptan-2-yl)-1-oxidanylidene-propan-2-yl]amino]-5H-pyrazolo[3,4-d]pyrimidin-4-one · ligand · 2 copies · chains A, B
- ZN · Zinc ion · metal · 2 copies · chains A, B
- MG · Magnesium ion · metal · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7F0I · phosphodiesterase-9A in complex with inhibitor 4b · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 7F0I · PDBe 7F0I
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