MolNFT v1 · #177864 · protein

Mycobacterium tuberculosis HIGA2 (form I)

7EWC · Putative antitoxin HIGA2: “Mycobacterium tuberculosis HIGA2 (form I)”. X-ray diffraction. MolNFT v1 #177864 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7EWC
Type: protein
Length: 275 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Putative antitoxin HIGA2
UniProt: O53467

Structure

x-ray diffraction · 4 distinct chains · 49% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Putative antitoxin HIGA2	protein	70	50% helix, 19% strand	O53467
B	Putative antitoxin HIGA2	protein	68	47% helix, 19% strand	O53467
C	Putative antitoxin HIGA2	protein	69	45% helix, 19% strand	O53467
D	Putative antitoxin HIGA2	protein	68	56% helix, 19% strand	O53467

Interfaces

5 interfaces between chains.

C–D · 1257 Å² buried · 24 hydrogen bonds · protein-protein
A–B · 1191 Å² buried · 24 hydrogen bonds · protein-protein
A–C · 346 Å² buried · 6 hydrogen bonds · protein-protein
A–D · 225 Å² buried · 1 hydrogen bond · protein-protein
B–C · 195 Å² buried · 2 hydrogen bonds · protein-protein

Compared structures

7EWC · Mycobacterium tuberculosis HigA2 (Form I) · the same entry in another collection · chain D against D, TM-score 1.00
O53467 · AlphaFold monomer V2.0 prediction for putative antitoxin HIGA2 (O53467) · a predicted model of the same protein · chain C against A, TM-score 0.89

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O53467
Elsewhere: RCSB PDB 7EWC · PDBe 7EWC · UniProt O53467

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