MolNFT v1 · #177818 · protein
Structural and mechanistic studies of a novel non-heme iron EPIMERASE/LYASE and its utilization in chemoselective synthesis.
7EUZ · Cupin domain-containing protein: “Structural and mechanistic studies of a novel non-heme iron EPIMERASE/LYASE and its utilization in…”. X-ray diffraction, 3 ligands (JD3, FE, PO3), 2 pockets (best druggability 0.69). MolNFT v1…
- PDB
- 7EUZ
- Type
- protein
- Length
- 233 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cupin domain-containing protein
- UniProt
- L7PIL3
- Ligands
- JD3, FE, PO3
- Pockets
- 2 · best druggability 0.69
Structure
x-ray diffraction · 2 distinct chains · 3% helix, 51% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cupin domain-containing protein | protein | 118 | 3% helix, 51% strand | L7PIL3 |
| B | Cupin domain-containing protein | protein | 115 | 3% helix, 51% strand | L7PIL3 |
Ligands and binding sites
- JD3 · (2S,3R)-2-azanyl-3-(1H-indol-3-yl)butanoic acid · ligand · chains B
- FE · Fe (III) ion · metal · 2 copies · chains A, B
- PO3 · Phosphite ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 353 | 0.69 | 0.82 | 43 | JD3 |
| 2 | 223 | 0.64 | 0.82 | 42 | PO3 |
Interfaces
1 interface between chains.
- A–B · 1514 Ų buried · 14 hydrogen bonds · protein-protein
Compared structures
- 7EUZ · Structural and mechanistic studies of a novel non-heme iron epimerase/lyase and its… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt L7PIL3
- Elsewhere: RCSB PDB 7EUZ · PDBe 7EUZ · UniProt L7PIL3
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.