MolNFT v1 · #1778 · protein
Chemotaxis receptor recognition by protein methyltransferase cher
1BC5 · Chemotaxis receptor methyltransferase: “Chemotaxis receptor recognition by protein methyltransferase cher”. X-ray diffraction, 3 ligands (ACE, SAH, CO), 1 pocket (best druggability 0.75). MolNFT v1 #1778 on GenesisL1: 3D structure…
- PDB
- 1BC5
- Type
- protein
- Length
- 274 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Chemotaxis receptor methyltransferase; Chemotaxis receptor
- EC
- 2.1.1.80
- UniProt
- P07801
- Ligands
- ACE, SAH, CO
- Pockets
- 1 · best druggability 0.75
Structure
x-ray diffraction · 2 distinct chains · 43% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Chemotaxis receptor methyltransferase (EC 2.1.1.80) | protein | 269 | 44% helix, 18% strand | P07801 |
| T | Chemotaxis receptor | protein | 5 | 0% helix, 40% strand | — |
Ligands and binding sites
- ACE · Acetyl group · ligand · chains A, T
- SAH · S-adenosyl-L-homocysteine · ligand · chains A
- CO · Cobalt (II) ion · metal · chains A, T
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 130 | 0.75 | 0.94 | 30 | SAH |
Interfaces
1 interface between chains.
- A–T · 531 Ų buried · 10 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 covalent (covalent ligand).
Compared structures
- 1BC5 · Chemotaxis receptor recognition by protein methyltransferase cher · the same entry in another collection · chain A against A, TM-score 1.00
- P07801 · AlphaFold monomer V2.0 prediction for chemotaxis protein methyltransferase (P07801) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P07801
- Elsewhere: RCSB PDB 1BC5 · PDBe 1BC5 · UniProt P07801
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