MolNFT v1 · #177785 · protein
The FK1 domain of FKBP51 in complex with peptide-inhibitor hit qfpfv
7ETT: “The FK1 domain of FKBP51 in complex with peptide-inhibitor hit qfpfv”. X-ray diffraction. MolNFT v1 #177785 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7ETT
- Type
- protein
- Length
- 132 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Peptide-inhibitor hit; Peptidyl-prolyl cis-trans isomerase FKBP5
- EC
- 5.2.1.8
- UniProt
- Q13451
Structure
x-ray diffraction · 2 distinct chains · 16% helix, 36% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | Peptide-inhibitor hit | protein | 5 | 0% helix, 20% strand | — |
| A | Peptidyl-prolyl cis-trans isomerase FKBP5 (EC 5.2.1.8) | protein | 127 | 17% helix, 37% strand | Q13451 |
Interfaces
1 interface between chains.
- B–A · 361 Ų buried · 2 hydrogen bonds · protein-protein
Compared structures
- 7ETT · The FK1 domain of FKBP51 in complex with peptide-inhibitor hit QFPFV · the same entry in another collection · chain B against B, TM-score 1.00
- Q13451 · AlphaFold monomer V2.0 prediction for peptidyl-prolyl cis-trans isomerase FKBP5 (Q13451) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q13451
- Elsewhere: RCSB PDB 7ETT · PDBe 7ETT · UniProt Q13451
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.