MolNFT v1 · #177764 · protein + DNA
Crystal structure of arabidopsis TEM1 B3-DNA complex
7ET6 · AP2/ERF and B3 domain-containing transcription repressor…: “Crystal structure of arabidopsis TEM1 B3-DNA complex”. X-ray diffraction, 2 pockets (best druggability 0.67). MolNFT v1 #177764 on GenesisL1: 3D structure, binding sites…
- PDB
- 7ET6
- Type
- protein + DNA
- Length
- 241 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- AP2/ERF and B3 domain-containing transcription repressor TEM1; Ft-RY14-F; Ft-RY14-R
- UniProt
- Q9C6M5
- Pockets
- 2 · best druggability 0.67
Structure
x-ray diffraction · 4 distinct chains · 16% helix, 39% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| D | AP2/ERF and B3 domain-containing transcription repressor TEM1 | protein | 109 | 14% helix, 39% strand | Q9C6M5 |
| A | AP2/ERF and B3 domain-containing transcription repressor TEM1 | protein | 102 | 18% helix, 39% strand | Q9C6M5 |
| E | Ft-RY14-F | dna | 15 | — | — |
| F | Ft-RY14-R | dna | 15 | — | — |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 443 | 0.67 | 0.79 | 32 | empty |
| 2 | 59 | 0.26 | 0.73 | 13 | empty |
Interfaces
5 interfaces between chains.
- E–F · 661 Ų buried · 67 hydrogen bonds · nucleic-nucleic
- A–E · 534 Ų buried · 9 hydrogen bonds · protein-nucleic
- A–F · 440 Ų buried · 8 hydrogen bonds · protein-nucleic
- D–E · 213 Ų buried · 5 hydrogen bonds · protein-nucleic
- D–F · 157 Ų buried · 5 hydrogen bonds · protein-nucleic
Compared structures
- 7ET6 · Crystal structure of Arabidopsis TEM1 B3-DNA complex · the same entry in another collection · chain D against D, TM-score 1.00
- Q9C6M5 · AlphaFold monomer V2.0 prediction for AP2/ERF and B3 domain- containing transcription… · a predicted model of the same protein · chain A against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9C6M5
- Elsewhere: RCSB PDB 7ET6 · PDBe 7ET6 · UniProt Q9C6M5
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