MolNFT v1 · #177742 · protein

Acinetobacter baumannii membrane-bound lytic murein transglycosylase a

7ESJ: “Acinetobacter baumannii membrane-bound lytic murein transglycosylase a”. X-ray diffraction, 6 pockets (best druggability 0.66). MolNFT v1 #177742 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7ESJ
Type: protein
Length: 690 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Membrane-bound lytic murein transglycosylase a
Pockets: 6 · best druggability 0.66

Structure

x-ray diffraction · 1 distinct chain · 27% helix, 32% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Membrane-bound lytic murein transglycosylase a	protein	345	27% helix, 32% strand	—

Pockets

6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	675	0.66	0.75	74	empty
2	100	0.55	0.84	22	empty
3	110	0.55	0.83	20	empty
4	224	0.48	0.74	31	empty
5	114	0.35	0.73	24	empty

Interfaces

1 interface between chains.

A–B · 263 Å² buried · 1 hydrogen bond · protein-protein

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

7ESJ · Acinetobacter baumannii membrane-bound lytic murein transglycosylase A · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 7ESJ · PDBe 7ESJ

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