MolNFT v1 · #177737 · protein

The crystal structure of human DHFR from biortus

7ESE: “The crystal structure of human DHFR from biortus”. X-ray diffraction, 1 ligand (NAP). MolNFT v1 #177737 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7ESE
Type: protein
Length: 186 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P00374
Ligands: NAP

Structure

x-ray diffraction · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	186	—	P00374

Ligands and binding sites

NAP · Nadp nicotinamide-adenine-dinucleotide phosphate · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7ESE · The Crystal Structure of human DHFR from Biortus · the same entry in another collection · chain A against A, TM-score 0.99
P00374 · AlphaFold monomer V2.0 prediction for dihydrofolate reductase (P00374) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P00374
Elsewhere: RCSB PDB 7ESE · PDBe 7ESE · UniProt P00374

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