MolNFT v1 · #177526 · protein
Crystal structure of mycobacterium tuberculosis tryptophanyl-tRNA synthetase
7EL8 · Tryptophan--tRNA ligase: “Crystal structure of mycobacterium tuberculosis tryptophanyl-tRNA synthetase”. X-ray diffraction, 3 pockets (best druggability 0.75). MolNFT v1 #177526 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 7EL8
- Type
- protein
- Length
- 316 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Tryptophan--tRNA ligase
- EC
- 6.1.1.2
- UniProt
- A0A045IZS3
- Pockets
- 3 · best druggability 0.75
Structure
x-ray diffraction · 1 distinct chain · 55% helix, 8% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tryptophan--tRNA ligase (EC 6.1.1.2) | protein | 316 | 55% helix, 8% strand | A0A045IZS3 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 499 | 0.75 | 0.83 | 53 | empty |
| 2 | 70 | 0.32 | 0.75 | 19 | empty |
| 3 | 56 | 0.28 | 0.74 | 9 | empty |
Compared structures
- 7EL8 · Crystal structure of Mycobacterium tuberculosis tryptophanyl-tRNA synthetase · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A045IZS3
- Elsewhere: RCSB PDB 7EL8 · PDBe 7EL8 · UniProt A0A045IZS3
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