MolNFT v1 · #177351 · protein
Crystal structure of cell shape-determining protein mrec
7EFT · Cell shape protein mrec: “Crystal structure of cell shape-determining protein mrec”. X-ray diffraction, 1 ligand (CL), 5 pockets (best druggability 0.60). MolNFT v1 #177351 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 7EFT
- Type
- protein
- Length
- 426 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cell shape protein mrec
- UniProt
- A0A024L8Y8
- Ligands
- CL
- Pockets
- 5 · best druggability 0.60
Structure
x-ray diffraction · 2 distinct chains · 20% helix, 35% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cell shape protein mrec | protein | 200 | 18% helix, 38% strand | A0A024L8Y8 |
| B | Cell shape protein mrec | protein | 226 | 23% helix, 33% strand | A0A024L8Y8 |
Ligands and binding sites
- CL · Chloride ion · ion · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 371 | 0.60 | 0.76 | 40 | empty |
| 2 | 301 | 0.56 | 0.76 | 34 | empty |
| 3 | 133 | 0.49 | 0.79 | 18 | empty |
| 4 | 57 | 0.30 | 0.76 | 14 | empty |
| 5 | 55 | 0.28 | 0.75 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 2294 Ų buried · 23 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 7EFT · Crystal structure of cell shape-determining protein MreC · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A024L8Y8
- Elsewhere: RCSB PDB 7EFT · PDBe 7EFT · UniProt A0A024L8Y8
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