MolNFT v1 · #177319 · protein

Cyanophage PAM1 tail machine

7EEQ · Needle head proteins: “Cyanophage PAM1 tail machine”. Electron microscopy, 20 pockets (best druggability 0.87). MolNFT v1 #177319 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7EEQ
Type: protein
Length: 4,488 residues
Chains: 24
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Needle head proteins; Tailspike head-binding domain
Pockets: 20 · best druggability 0.87

Structure

electron microscopy · 2 distinct chains · 1% helix, 31% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
1, 2, 3, 4, 5, 6	Needle head proteins	protein	442	1% helix, 33% strand	—
A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R	Tailspike head-binding domain	protein	102	4% helix, 24% strand	—

Pockets

20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	607	0.87	0.92	93	empty
2	787	0.87	0.89	106	empty
3	1082	0.85	0.86	119	empty
4	990	0.85	0.86	120	empty
5	1035	0.85	0.85	121	empty

Interfaces

42 interfaces between chains.

2–3 · 1971 Å² buried · 23 hydrogen bonds · protein-protein
1–6 · 1967 Å² buried · 23 hydrogen bonds · protein-protein
5–6 · 1965 Å² buried · 23 hydrogen bonds · protein-protein
1–2 · 1964 Å² buried · 23 hydrogen bonds · protein-protein
4–5 · 1962 Å² buried · 23 hydrogen bonds · protein-protein

Compared structures

7EEQ · Cyanophage Pam1 tail machine · the same entry in another collection · chain 1 against 1, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 7EEQ · PDBe 7EEQ

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