MolNFT v1 · #177317 · RNA
Bulged-G motif composed of RNA, DNA and 2'-O-methyl RNA
7EEO · DNA/RNA (27-mer): “Bulged-G motif composed of RNA, DNA and 2'-O-methyl RNA”. X-ray diffraction, 1 ligand (NCO), 1 pocket (best druggability 0.28). MolNFT v1 #177317 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7EEO
- Type
- RNA
- Length
- 47 nucleotides
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- DNA/RNA (27-mer)
- Ligands
- NCO
- Pockets
- 1 · best druggability 0.28
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA/RNA (27-mer) | rna | 24 | — | — |
| B | DNA/RNA (27-mer) | rna | 23 | — | — |
Ligands and binding sites
- NCO · Cobalt hexammine(iii) · ligand · 3 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 75 | 0.28 | 0.73 | 12 | empty |
Interfaces
1 interface between chains.
- A–B · 102 Ų buried · 1 hydrogen bond · nucleic-nucleic
Modifications
Observed in the structure: 15 modified (nucleotide modification).
Compared structures
- 7EEO · Bulged-G motif composed of RNA, DNA and 2'-O-methyl RNA · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 7EEO · PDBe 7EEO
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.