MolNFT v1 · #177304 · protein

Cyanophage PAM1 tailspike receptor-binding domain

7EEA · Short-tailed cyanophage tailspike receptor-binding domain: “Cyanophage PAM1 tailspike receptor-binding domain”. X-ray diffraction, 19 pockets (best druggability 0.92). MolNFT v1 #177304 on GenesisL1: 3D structure, binding sites and…

PDB: 7EEA
Type: protein
Length: 1,934 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Short-tailed cyanophage tailspike receptor-binding domain
Pockets: 19 · best druggability 0.92

Structure

x-ray diffraction · 3 distinct chains · 4% helix, 46% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Short-tailed cyanophage tailspike receptor-binding domain	protein	645	4% helix, 46% strand	—
B	Short-tailed cyanophage tailspike receptor-binding domain	protein	643	5% helix, 47% strand	—
C	Short-tailed cyanophage tailspike receptor-binding domain	protein	646	4% helix, 45% strand	—

Pockets

19 pockets found on a 1 Å grid, 12 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1172	0.92	0.95	120	empty
2	287	0.83	0.94	43	empty
3	454	0.81	0.89	92	empty
4	94	0.76	0.97	18	empty
5	82	0.71	0.95	18	empty

Interfaces

3 interfaces between chains.

A–B · 3918 Å² buried · 68 hydrogen bonds · protein-protein
A–C · 3911 Å² buried · 62 hydrogen bonds · protein-protein
B–C · 3887 Å² buried · 63 hydrogen bonds · protein-protein

Compared structures

7EEA · Cyanophage Pam1 tailspike receptor-binding domain · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 7EEA · PDBe 7EEA

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