MolNFT v1 · #177203 · protein

The X-ray crystallographic structure of glycogen debranching enzyme from sulfolobus solfataricus STB09

7EAV: “The X-ray crystallographic structure of glycogen debranching enzyme from sulfolobus solfataricus STB09”. X-ray diffraction, 16 pockets (best druggability 0.81). MolNFT v1 #177203 on GenesisL1: 3D structure, binding sites and pockets…

PDB: 7EAV
Type: protein
Length: 1,429 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Glycogen debranching enzyme
UniProt: P95868
Pockets: 16 · best druggability 0.81

Structure

x-ray diffraction · 2 distinct chains · 23% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Glycogen debranching enzyme	protein	715	24% helix, 20% strand	P95868
B	Glycogen debranching enzyme	protein	714	23% helix, 21% strand	P95868

Pockets

16 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1100	0.81	0.82	88	empty
2	1176	0.80	0.81	99	empty
3	490	0.68	0.79	54	empty
4	616	0.68	0.77	55	empty
5	156	0.53	0.80	20	empty

Interfaces

1 interface between chains.

A–B · 1484 Å² buried · 15 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 3 disulfide (disulfide).

Compared structures

7EAV · The X-ray crystallographic structure of glycogen debranching enzyme from Sulfolobus… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P95868
Elsewhere: RCSB PDB 7EAV · PDBe 7EAV · UniProt P95868

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