MolNFT v1 · #177201 · protein
Crystal structure of human pyruvate dehydrogenase kinase 4 in complex with compound 1
7EAT: “Crystal structure of human pyruvate dehydrogenase kinase 4 in complex with compound 1”. X-ray diffraction, 2 ligands (W6P, SO4). MolNFT v1 #177201 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7EAT
- Type
- protein
- Length
- 674 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q16654
- Ligands
- W6P, SO4
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 337 | — | Q16654 |
| B | — | protein | 337 | — | Q16654 |
Ligands and binding sites
- W6P · 1,3-dihydro-2H-indol-2-one · ligand · 2 copies · chains A, B
- SO4 · Sulfate ion · ion · 4 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7EAT · Crystal structure of human pyruvate dehydrogenase kinase 4 in complex with compound 1 · the same entry in another collection · chain A against A, TM-score 1.00
- Q16654 · AlphaFold monomer V2.0 prediction for [pyruvate dehydrogenase (acetyl-transferring)]… · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q16654
- Elsewhere: RCSB PDB 7EAT · PDBe 7EAT · UniProt Q16654
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