MolNFT v1 · #177141 · protein
ECOT38I restriction endonuclease
7E8R: “ECOT38I restriction endonuclease”. X-ray diffraction, 4 pockets (best druggability 0.49). MolNFT v1 #177141 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7E8R
- Type
- protein
- Length
- 346 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- ECOT38I restriction endonuclease
- UniProt
- Q83VS8
- Pockets
- 4 · best druggability 0.49
Structure
x-ray diffraction · 1 distinct chain · 53% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | ECOT38I restriction endonuclease | protein | 346 | 53% helix, 10% strand | Q83VS8 |
Ligands and binding sites
- GOL · Glycerol · additive · 10 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 147 | 0.49 | 0.78 | 24 | empty |
| 2 | 108 | 0.46 | 0.79 | 16 | empty |
| 3 | 151 | 0.45 | 0.76 | 25 | GOL |
| 4 | 79 | 0.38 | 0.78 | 19 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 7E8R · EcoT38I restriction endonuclease · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q83VS8
- Elsewhere: RCSB PDB 7E8R · PDBe 7E8R · UniProt Q83VS8
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