MolNFT v1 · #177133 · protein
Crystal structure of proteinaceous RNase P (prorp) from thermococcus celer
7E8J · RNA-free ribonuclease P: “Crystal structure of proteinaceous RNase P (prorp) from thermococcus celer”. X-ray diffraction, 2 pockets (best druggability 0.49). MolNFT v1 #177133 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 7E8J
- Type
- protein
- Length
- 389 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- RNA-free ribonuclease P
- EC
- 3.1.26.5
- UniProt
- A0A218P4J1
- Pockets
- 2 · best druggability 0.49
Structure
x-ray diffraction · 2 distinct chains · 65% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | RNA-free ribonuclease P (EC 3.1.26.5) | protein | 197 | 64% helix, 11% strand | A0A218P4J1 |
| B | RNA-free ribonuclease P (EC 3.1.26.5) | protein | 192 | 66% helix, 11% strand | A0A218P4J1 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 223 | 0.49 | 0.75 | 29 | empty |
| 2 | 187 | 0.48 | 0.76 | 28 | empty |
Interfaces
1 interface between chains.
- A–B · 1860 Ų buried · 11 hydrogen bonds · protein-protein
Compared structures
- 7E8J · Crystal structure of Proteinaceous RNase P (PRORP) from Thermococcus celer · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A218P4J1
- Elsewhere: RCSB PDB 7E8J · PDBe 7E8J · UniProt A0A218P4J1
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