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MolNFT v1 · #17695 · protein

Structural insights into the inter-domain chaperoning of tandem PDZ domains in glutamate receptor interacting proteins

1P1D: “Structural insights into the inter-domain chaperoning of tandem PDZ domains in glutamate receptor interacting…”. Solution nmr, 2 pockets (best druggability 0.58). MolNFT v1 #17695 on GenesisL1: 3D structure, binding sites and…

PDB
1P1D
Type
protein
Length
196 residues
Chains
1
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Glutamate receptor interacting protein
UniProt
P97879
Pockets
2 · best druggability 0.58

Structure

solution nmr · 1 distinct chain · 15% helix, 30% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AGlutamate receptor interacting proteinprotein19615% helix, 30% strandP97879

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1670.580.8824empty
21920.510.7725empty

Compared structures

  • 1P1D · Structural Insights into the Inter-domain Chaperoning of Tandem PDZ Domains in Glutamate… · the same entry in another collection · chain A against A, TM-score 1.00
  • P97879 · AlphaFold monomer V2.0 prediction for glutamate receptor-interacting protein 1 (P97879) · a predicted model of the same protein · chain A against A, TM-score 0.83

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