MolNFT v1 · #176933 · protein
Crystal structure of sdr family NAD(P)-dependent oxidoreductase from exiguobacterium
7E28: “Crystal structure of sdr family NAD(P)-dependent oxidoreductase from exiguobacterium”. X-ray diffraction, 4 pockets (best druggability 0.53). MolNFT v1 #176933 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7E28
- Type
- protein
- Length
- 450 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Oxidoreductase
- UniProt
- Q6BDS0
- Pockets
- 4 · best druggability 0.53
Structure
x-ray diffraction · 2 distinct chains · 46% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Oxidoreductase | protein | 224 | 47% helix, 21% strand | Q6BDS0 |
| B | Oxidoreductase | protein | 226 | 46% helix, 20% strand | Q6BDS0 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 231 | 0.53 | 0.77 | 37 | empty |
| 2 | 157 | 0.46 | 0.76 | 26 | empty |
| 3 | 100 | 0.45 | 0.79 | 19 | empty |
| 4 | 58 | 0.26 | 0.73 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 1959 Ų buried · 12 hydrogen bonds · protein-protein
Compared structures
- 7E28 · Crystal structure of SDR family NAD(P)-dependent oxidoreductase from Exiguobacterium · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6BDS0
- Elsewhere: RCSB PDB 7E28 · PDBe 7E28 · UniProt Q6BDS0
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