MolNFT v1 · #176913 · protein

Crystal structure of apo form phlh

7E1L · DUF1956 domain-containing protein: “Crystal structure of apo form phlh”. X-ray diffraction, 5 pockets (best druggability 0.84). MolNFT v1 #176913 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7E1L
Type: protein
Length: 401 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: DUF1956 domain-containing protein
UniProt: Q4JIX5
Pockets: 5 · best druggability 0.84

Structure

x-ray diffraction · 2 distinct chains · 75% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DUF1956 domain-containing protein	protein	199	78% helix, 0% strand	Q4JIX5
B	DUF1956 domain-containing protein	protein	202	71% helix, 0% strand	Q4JIX5

Pockets

5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	661	0.84	0.87	60	empty
2	906	0.79	0.81	78	empty
3	256	0.65	0.82	30	empty
4	76	0.43	0.80	12	empty
5	66	0.30	0.74	12	empty

Interfaces

1 interface between chains.

A–B · 1870 Å² buried · 9 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 6 modified (engineered).

Compared structures

7E1L · Crystal structure of apo form PhlH · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q4JIX5
Elsewhere: RCSB PDB 7E1L · PDBe 7E1L · UniProt Q4JIX5

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