MolNFT v1 · #176820 · protein

Pseudomonas aeruginosa tset-tsit complex

7DYM · Tox-rease-5 domain-containing protein: “Pseudomonas aeruginosa tset-tsit complex”. X-ray diffraction, 5 pockets (best druggability 0.54). MolNFT v1 #176820 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7DYM
Type: protein
Length: 409 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Tox-rease-5 domain-containing protein; IMM52 domain-containing protein
UniProt: Q9HXA6, Q9HXA5
Pockets: 5 · best druggability 0.54

Structure

x-ray diffraction · 2 distinct chains · 38% helix, 22% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Tox-rease-5 domain-containing protein	protein	171	40% helix, 20% strand	Q9HXA6
B	IMM52 domain-containing protein	protein	238	37% helix, 23% strand	Q9HXA5

Pockets

5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	206	0.54	0.79	25	empty
2	180	0.46	0.75	28	empty
3	116	0.35	0.73	18	empty
4	55	0.34	0.78	19	empty
5	83	0.32	0.74	16	empty

Interfaces

1 interface between chains.

A–B · 1147 Å² buried · 8 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

7DYM · Pseudomonas aeruginosa TseT-TsiT complex · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9HXA6
Every structure of UniProt Q9HXA5
Elsewhere: RCSB PDB 7DYM · PDBe 7DYM · UniProt Q9HXA6 · UniProt Q9HXA5

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