MolNFT v1 · #176815 · protein
Crystal structure of cyanobacterial circadian clock protein kaic
7DYE · Circadian clock protein kinase kaic: “Crystal structure of cyanobacterial circadian clock protein kaic”. X-ray diffraction, 2 ligands (ATP, MG), 11 pockets (best druggability 0.86). MolNFT v1 #176815 on GenesisL1: 3D structure…
- PDB
- 7DYE
- Type
- protein
- Length
- 916 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Circadian clock protein kinase kaic
- EC
- 2.7.11.1
- UniProt
- Q79PF4
- Ligands
- ATP, MG
- Pockets
- 11 · best druggability 0.86
Structure
x-ray diffraction · 2 distinct chains · 30% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Circadian clock protein kinase kaic (EC 2.7.11.1) | protein | 458 | 30% helix, 27% strand | Q79PF4 |
| B | Circadian clock protein kinase kaic (EC 2.7.11.1) | protein | 458 | 31% helix, 27% strand | Q79PF4 |
Ligands and binding sites
- ATP · Adenosine-5'-triphosphate · ligand · 4 copies · chains A, B
- MG · Magnesium ion · metal · 4 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
11 pockets found on a 1 Å grid, 10 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1149 | 0.86 | 0.87 | 163 | ATP, MG |
| 2 | 367 | 0.73 | 0.84 | 74 | empty |
| 3 | 172 | 0.72 | 0.90 | 31 | ATP, MG |
| 4 | 178 | 0.70 | 0.88 | 33 | empty |
| 5 | 240 | 0.68 | 0.84 | 45 | empty |
Interfaces
1 interface between chains.
- A–B · 2664 Ų buried · 34 hydrogen bonds · protein-protein
Compared structures
- 7DYE · Crystal Structure of Cyanobacterial Circadian Clock Protein KaiC · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q79PF4
- Elsewhere: RCSB PDB 7DYE · PDBe 7DYE · UniProt Q79PF4
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.