MolNFT v1 · #176727 · protein

Crystal structure of apo (heme-free) pefr

7DVS · Marr family transcriptional regulator: “Crystal structure of apo (heme-free) pefr”. X-ray diffraction, 2 pockets (best druggability 0.76). MolNFT v1 #176727 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7DVS
Type: protein
Length: 502 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Marr family transcriptional regulator
UniProt: R4Z9I5
Pockets: 2 · best druggability 0.76

Structure

x-ray diffraction · 4 distinct chains · 64% helix, 9% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Marr family transcriptional regulator	protein	139	68% helix, 9% strand	R4Z9I5
B	Marr family transcriptional regulator	protein	138	66% helix, 9% strand	R4Z9I5
C	Marr family transcriptional regulator	protein	116	63% helix, 10% strand	R4Z9I5
D	Marr family transcriptional regulator	protein	109	56% helix, 10% strand	R4Z9I5

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	965	0.76	0.78	68	empty
2	113	0.39	0.74	24	empty

Interfaces

3 interfaces between chains.

A–B · 1427 Å² buried · 10 hydrogen bonds · protein-protein
C–D · 564 Å² buried · 2 hydrogen bonds · protein-protein
A–C · 464 Å² buried · 4 hydrogen bonds · protein-protein

Compared structures

7DVS · Crystal structure of Apo (heme-free) PefR · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt R4Z9I5
Elsewhere: RCSB PDB 7DVS · PDBe 7DVS · UniProt R4Z9I5

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.