MolNFT v1 · #176474 · protein
MRNA-decapping enzyme G5RP with inhibitor INSP6 complex
7DNU · MRNA-decapping protein G5R: “MRNA-decapping enzyme G5RP with inhibitor INSP6 complex”. X-ray diffraction, 1 ligand (IHP), 1 pocket (best druggability 0.62). MolNFT v1 #176474 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 7DNU
- Type
- protein
- Length
- 247 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- MRNA-decapping protein G5R
- EC
- 3.1.3.-, 3.6.1.52
- UniProt
- P32092
- Ligands
- IHP
- Pockets
- 1 · best druggability 0.62
Structure
x-ray diffraction · 1 distinct chain · 43% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | MRNA-decapping protein G5R (EC 3.1.3.-, 3.6.1.52) | protein | 247 | 43% helix, 23% strand | P32092 |
Ligands and binding sites
- IHP · Inositol hexakisphosphate · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 534 | 0.62 | 0.75 | 45 | empty |
Compared structures
- 7DNU · mRNA-decapping enzyme g5Rp with inhibitor insp6 complex · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P32092
- Elsewhere: RCSB PDB 7DNU · PDBe 7DNU · UniProt P32092
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