MolNFT v1 · #176473 · protein

MRNA-decapping enzyme G5RP

7DNT · MRNA-decapping protein G5R: “MRNA-decapping enzyme G5RP”. X-ray diffraction, 1 pocket (best druggability 0.56). MolNFT v1 #176473 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7DNT
Type: protein
Length: 243 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: MRNA-decapping protein G5R
EC: 3.1.3.-, 3.6.1.52
UniProt: P32092
Pockets: 1 · best druggability 0.56

Structure

x-ray diffraction · 1 distinct chain · 43% helix, 24% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	MRNA-decapping protein G5R (EC 3.1.3.-, 3.6.1.52)	protein	243	43% helix, 24% strand	P32092

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	381	0.56	0.74	46	empty

Modifications

Observed in the structure: 9 modified (engineered).

Compared structures

7DNT · mRNA-decapping enzyme g5Rp · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P32092
Elsewhere: RCSB PDB 7DNT · PDBe 7DNT · UniProt P32092

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