MolNFT v1 · #176223 · protein

NMR structure of TUSP2-rp

7DFE · B6 protein: “NMR structure of TUSP2-rp”. Solution nmr, 4 pockets (best druggability 0.50). MolNFT v1 #176223 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7DFE
Type: protein
Length: 284 residues
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: B6 protein
UniProt: A5Y0M2
Pockets: 4 · best druggability 0.50

Structure

solution nmr · 1 distinct chain · 65% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	B6 protein	protein	142	65% helix, 0% strand	A5Y0M2

Pockets

4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	59	0.50	0.86	14	empty
2	98	0.46	0.79	19	empty
3	156	0.41	0.74	29	empty
4	152	0.39	0.73	24	empty

Interfaces

1 interface between chains.

A–B · 1257 Å² buried · 11 hydrogen bonds · protein-protein

Compared structures

7DFE · NMR structure of TuSp2-RP · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A5Y0M2
Elsewhere: RCSB PDB 7DFE · PDBe 7DFE · UniProt A5Y0M2

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