MolNFT v1 · #176158 · protein
Crystal structure of fungal antifreeze protein with intermediate activity
7DDB: “Crystal structure of fungal antifreeze protein with intermediate activity”. X-ray diffraction, 1 ligand (MG), 2 pockets (best druggability 0.53). MolNFT v1 #176158 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7DDB
- Type
- protein
- Length
- 446 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Antifreeze protein
- UniProt
- Q76CE7
- Ligands
- MG
- Pockets
- 2 · best druggability 0.53
Structure
x-ray diffraction · 1 distinct chain · 16% helix, 42% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Antifreeze protein | protein | 223 | 16% helix, 42% strand | Q76CE7 |
Ligands and binding sites
- MG · Magnesium ion · metal · 3 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 195 | 0.53 | 0.78 | 32 | empty |
| 2 | 127 | 0.41 | 0.75 | 30 | empty |
Interfaces
1 interface between chains.
- A–B · 246 Ų buried · 1 hydrogen bond · protein-protein
Compared structures
- 7DDB · Crystal structure of fungal antifreeze protein with intermediate activity · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q76CE7
- Elsewhere: RCSB PDB 7DDB · PDBe 7DDB · UniProt Q76CE7
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