MolNFT v1 · #176147 · protein
Crystal structure of the N-terminal domain of tagh from bacillus subtilis
7DD0 · Teichoic acids export ATP-binding protein tagh: “Crystal structure of the N-terminal domain of tagh from bacillus subtilis”. X-ray diffraction, 14 pockets (best druggability 0.83). MolNFT v1 #176147 on GenesisL1: 3D structure…
- PDB
- 7DD0
- Type
- protein
- Length
- 997 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Teichoic acids export ATP-binding protein tagh
- EC
- 7.5.2.4
- UniProt
- P42954
- Pockets
- 14 · best druggability 0.83
Structure
x-ray diffraction · 4 distinct chains · 43% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Teichoic acids export ATP-binding protein tagh (EC 7.5.2.4) | protein | 244 | 45% helix, 27% strand | P42954 |
| B | Teichoic acids export ATP-binding protein tagh (EC 7.5.2.4) | protein | 260 | 41% helix, 25% strand | P42954 |
| C | Teichoic acids export ATP-binding protein tagh (EC 7.5.2.4) | protein | 252 | 41% helix, 26% strand | P42954 |
| D | Teichoic acids export ATP-binding protein tagh (EC 7.5.2.4) | protein | 241 | 43% helix, 27% strand | P42954 |
Pockets
14 pockets found on a 1 Å grid, 8 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 745 | 0.83 | 0.87 | 108 | empty |
| 2 | 530 | 0.79 | 0.86 | 83 | empty |
| 3 | 305 | 0.71 | 0.85 | 69 | empty |
| 4 | 331 | 0.71 | 0.84 | 37 | empty |
| 5 | 90 | 0.71 | 0.94 | 25 | empty |
Interfaces
6 interfaces between chains.
- B–D · 2256 Ų buried · 26 hydrogen bonds · protein-protein
- A–C · 1878 Ų buried · 25 hydrogen bonds · protein-protein
- C–D · 307 Ų buried · 1 hydrogen bond · protein-protein
- A–B · 285 Ų buried · 1 hydrogen bond · protein-protein
- A–D · 227 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 7DD0 · Crystal structure of the N-terminal domain of TagH from Bacillus subtilis · the same entry in another collection · chain D against D, TM-score 1.00
- P42954 · AlphaFold monomer V2.0 prediction for teichoic acids export ATP- binding protein tagh… · a predicted model of the same protein · chain A against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P42954
- Elsewhere: RCSB PDB 7DD0 · PDBe 7DD0 · UniProt P42954
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.