MolNFT v1 · #176127 · protein
Crystal structure of EHMT2 set domain in complex with compound 10
7DCF: “Crystal structure of EHMT2 set domain in complex with compound 10”. X-ray diffraction, 2 ligands (H30, ZN). MolNFT v1 #176127 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7DCF
- Type
- protein
- Length
- 521 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q96KQ7
- Ligands
- H30, ZN
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 261 | — | Q96KQ7 |
| B | — | protein | 260 | — | Q96KQ7 |
Ligands and binding sites
- H30 · 5'-methoxy-6'-(1-methyl-2,3,4,7-tetrahydroazepin-5-yl) spiro[cyclobutane-1,3'-indole]-2'-amine · ligand · 2 copies · chains A, B
- ZN · Zinc ion · metal · 8 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7DCF · Crystal structure of EHMT2 SET domain in complex with compound 10 · the same entry in another collection · chain A against A, TM-score 1.00
- Q96KQ7 · AlphaFold monomer V2.0 prediction for histone-lysine N-methyltransferase EHMT2 (Q96KQ7) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q96KQ7
- Elsewhere: RCSB PDB 7DCF · PDBe 7DCF · UniProt Q96KQ7
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.