MolNFT v1 · #176059 · protein
Structure of 6-hydroxy-3-succinoyl-pyridine 3-monooxygenase (hspb) from pseudomonas putida S16
7DA9 · 6-hydroxy-3-succinoylpyridine 3-monooxygenase hspb: “Structure of 6-hydroxy-3-succinoyl-pyridine 3-monooxygenase (hspb) from pseudomonas putida S16”. X-ray diffraction, 7 pockets (best druggability 0.84). MolNFT v1 #176059 on…
- PDB
- 7DA9
- Type
- protein
- Length
- 776 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 6-hydroxy-3-succinoylpyridine 3-monooxygenase hspb
- EC
- 1.14.13.163
- UniProt
- F8G0M4
- Pockets
- 7 · best druggability 0.84
Structure
x-ray diffraction · 1 distinct chain · 39% helix, 28% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | 6-hydroxy-3-succinoylpyridine 3-monooxygenase hspb (EC 1.14.13.163) | protein | 388 | 39% helix, 28% strand | F8G0M4 |
Pockets
7 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 715 | 0.84 | 0.87 | 88 | empty |
| 2 | 833 | 0.82 | 0.85 | 90 | empty |
| 3 | 397 | 0.81 | 0.89 | 34 | empty |
| 4 | 376 | 0.61 | 0.77 | 29 | empty |
| 5 | 73 | 0.33 | 0.75 | 12 | empty |
Interfaces
1 interface between chains.
- A–B · 896 Ų buried · 17 hydrogen bonds · protein-protein
Compared structures
- 7DA9 · Structure of 6-hydroxy-3-succinoyl-pyridine 3-monooxygenase (HspB) from Pseudomonas… · the same entry in another collection · chain A against A, TM-score 1.00
- F8G0M4 · AlphaFold monomer V2.0 prediction for 6-hydroxy-3-succinoylpyridine 3-monooxygenase hspb… · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt F8G0M4
- Elsewhere: RCSB PDB 7DA9 · PDBe 7DA9 · UniProt F8G0M4
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.