MolNFT v1 · #175942 · protein
Crystal structure of the SARS-cov-2 papain-like protease (plpro) C112S mutant
7D6H: “Crystal structure of the SARS-cov-2 papain-like protease (plpro) C112S mutant”. X-ray diffraction, 2 ligands (ZN, PO4), 2 pockets (best druggability 0.39). MolNFT v1 #175942 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 7D6H
- Type
- protein
- Length
- 316 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Papain-like protease
- EC
- 3.4.19.12
- UniProt
- P0DTC1
- Ligands
- ZN, PO4
- Pockets
- 2 · best druggability 0.39
Structure
x-ray diffraction · 1 distinct chain · 26% helix, 36% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Papain-like protease (EC 3.4.19.12) | protein | 316 | 26% helix, 36% strand | P0DTC1 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 77 | 0.39 | 0.78 | 19 | empty |
| 2 | 54 | 0.30 | 0.76 | 15 | empty |
Compared structures
- 7D6H · Crystal structure of the SARS-CoV-2 papain-like protease (PLPro) C112S mutant · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0DTC1
- Elsewhere: RCSB PDB 7D6H · PDBe 7D6H · UniProt P0DTC1
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