MolNFT v1 · #175898 · protein

Crstal structure msgatase with gln

7D54 · Glutamine amidotransferase class-I: “Crstal structure msgatase with gln”. X-ray diffraction, 1 ligand (GLN), 4 pockets (best druggability 0.64). MolNFT v1 #175898 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7D54
Type: protein
Length: 484 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Glutamine amidotransferase class-I
EC: 6.3.5.2
Ligands: GLN
Pockets: 4 · best druggability 0.64

Structure

x-ray diffraction · 1 distinct chain · 35% helix, 25% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Glutamine amidotransferase class-I (EC 6.3.5.2)	protein	242	35% helix, 25% strand	—

Ligands and binding sites

GLN · Glutamine · ligand · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	233	0.64	0.83	25	GLN
2	237	0.64	0.82	26	GLN
3	233	0.53	0.77	31	empty
4	150	0.45	0.76	28	empty

Interfaces

1 interface between chains.

A–B · 608 Å² buried · 12 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 modified (oxidation).

Compared structures

7D54 · Crstal structure MsGATase with Gln · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 7D54 · PDBe 7D54

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