MolNFT v1 · #175512 · protein

Crystal structure of the N-terminal tandem rrm domains of RBM45

7CSX · RNA-binding protein 45: “Crystal structure of the N-terminal tandem rrm domains of RBM45”. X-ray diffraction, 1 pocket (best druggability 0.44). MolNFT v1 #175512 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7CSX
Type: protein
Length: 169 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: RNA-binding protein 45
UniProt: Q8IUH3
Pockets: 1 · best druggability 0.44

Structure

x-ray diffraction · 1 distinct chain · 31% helix, 30% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	RNA-binding protein 45	protein	169	31% helix, 30% strand	Q8IUH3

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	153	0.44	0.75	31	empty

Compared structures

7CSX · Crystal structure of the N-terminal tandem RRM domains of RBM45 · the same entry in another collection · chain A against A, TM-score 1.00
Q8IUH3 · AlphaFold monomer V2.0 prediction for RNA-binding protein 45 (Q8IUH3) · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8IUH3
Elsewhere: RCSB PDB 7CSX · PDBe 7CSX · UniProt Q8IUH3

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