MolNFT v1 · #175431 · protein

Apo gmas without ligand

7CQL · Type III glutamate--ammonia ligase: “Apo gmas without ligand”. X-ray diffraction, 8 pockets (best druggability 0.75). MolNFT v1 #175431 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7CQL
Type: protein
Length: 1,263 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Type III glutamate--ammonia ligase
EC: 6.3.1.2
UniProt: A0A369R1N0
Pockets: 8 · best druggability 0.75

Structure

x-ray diffraction · 1 distinct chain · 39% helix, 22% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C	Type III glutamate--ammonia ligase (EC 6.3.1.2)	protein	421	39% helix, 22% strand	A0A369R1N0

Pockets

8 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	709	0.75	0.81	71	empty
2	738	0.74	0.80	77	empty
3	685	0.72	0.78	62	empty
4	660	0.70	0.77	54	empty
5	252	0.59	0.80	33	empty

Interfaces

2 interfaces between chains.

A–C · 1430 Å² buried · 25 hydrogen bonds · protein-protein
A–B · 1414 Å² buried · 23 hydrogen bonds · protein-protein

Compared structures

7CQL · Apo GmaS without ligand · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A369R1N0
Elsewhere: RCSB PDB 7CQL · PDBe 7CQL · UniProt A0A369R1N0

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