MolNFT v1 · #175338 · protein
Crystal structure of TEAD3 in complex with VT105
7CNL: “Crystal structure of TEAD3 in complex with VT105”. X-ray diffraction, 4 ligands (G9O, G9C, PO4). MolNFT v1 #175338 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7CNL
- Type
- protein
- Length
- 844 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q99594
- Ligands
- G9O, G9C, PO4, CL
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 210 | — | Q99594 |
| B | — | protein | 218 | — | Q99594 |
| C | — | protein | 206 | — | Q99594 |
| D | — | protein | 210 | — | Q99594 |
Ligands and binding sites
- G9O · N-oxidanyltetradecanamide · ligand · 2 copies · chains A, C
- G9C · N-[(1S)-1-pyridin-2-ylethyl]-8-[4-(trifluoromethyl) phenyl]quinoline-3-carboxamide · ligand · 2 copies · chains A, B, D
- PO4 · Phosphate ion · ion · 8 copies · chains A, C, B, D
- CL · Chloride ion · ion · 4 copies · chains A, C, D, B
- TRS · 2-amino-2-hydroxymethyl-propane-1,3-diol · additive · chains A, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7CNL · Crystal structure of TEAD3 in complex with VT105 · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q99594
- Elsewhere: RCSB PDB 7CNL · PDBe 7CNL · UniProt Q99594
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