MolNFT v1 · #175066 · protein
Crystal structure of the restriction DNA glycosylase R.CCOLI
7CFA · R.PAB1 family restriction endonuclease: “Crystal structure of the restriction DNA glycosylase R.CCOLI”. X-ray diffraction, 4 pockets (best druggability 0.64). MolNFT v1 #175066 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 7CFA
- Type
- protein
- Length
- 427 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- R.PAB1 family restriction endonuclease
- UniProt
- A0A697F4U6
- Pockets
- 4 · best druggability 0.64
Structure
x-ray diffraction · 2 distinct chains · 28% helix, 35% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | R.PAB1 family restriction endonuclease | protein | 234 | 26% helix, 36% strand | A0A697F4U6 |
| B | R.PAB1 family restriction endonuclease | protein | 193 | 31% helix, 33% strand | A0A697F4U6 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 444 | 0.64 | 0.77 | 53 | empty |
| 2 | 174 | 0.49 | 0.77 | 26 | empty |
| 3 | 143 | 0.40 | 0.74 | 21 | empty |
| 4 | 75 | 0.36 | 0.76 | 14 | empty |
Interfaces
1 interface between chains.
- A–B · 1544 Ų buried · 20 hydrogen bonds · protein-protein
Compared structures
- 7CFA · Crystal structure of the restriction DNA glycosylase R.CcoLI · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A697F4U6
- Elsewhere: RCSB PDB 7CFA · PDBe 7CFA · UniProt A0A697F4U6
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.