MolNFT v1 · #175028 · protein
Structure of a novel virulence regulation factor sghr
7CDV · Laci-type transcription factor: “Structure of a novel virulence regulation factor sghr”. X-ray diffraction, 6 pockets (best druggability 0.80). MolNFT v1 #175028 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7CDV
- Type
- protein
- Length
- 553 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Laci-type transcription factor
- UniProt
- A0A2I4PGE9
- Pockets
- 6 · best druggability 0.80
Structure
x-ray diffraction · 2 distinct chains · 40% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Laci-type transcription factor | protein | 277 | 40% helix, 21% strand | A0A2I4PGE9 |
| B | Laci-type transcription factor | protein | 276 | 40% helix, 21% strand | A0A2I4PGE9 |
Pockets
6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 462 | 0.80 | 0.88 | 57 | empty |
| 2 | 510 | 0.79 | 0.86 | 62 | empty |
| 3 | 451 | 0.67 | 0.79 | 54 | empty |
| 4 | 61 | 0.43 | 0.83 | 17 | empty |
| 5 | 64 | 0.42 | 0.82 | 19 | empty |
Interfaces
1 interface between chains.
- A–B · 1495 Ų buried · 5 hydrogen bonds · protein-protein
Compared structures
- 7CDV · STRUCTURE OF A NOVEL VIRULENCE REGULATION FACTOR SghR · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A2I4PGE9
- Elsewhere: RCSB PDB 7CDV · PDBe 7CDV · UniProt A0A2I4PGE9
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