MolNFT v1 · #17497 · protein + DNA
NMR structure of ACTD/5'-ccgttttgtgg-3' complex
1OVF · (5'-D(*CP*CP*GP*TP*TP*TP*TP*GP*TP*GP*G)-3'): “NMR structure of ACTD/5'-ccgttttgtgg-3' complex”. Solution nmr, 1 ligand (PXZ). MolNFT v1 #17497 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1OVF
- Type
- protein + DNA
- Length
- 21 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- (5'-D(*CP*CP*GP*TP*TP*TP*TP*GP*TP*GP*G)-3'); Actinomycin D
- Ligands
- PXZ
Structure
solution nmr · 2 distinct chains · 0% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | (5'-D(*CP*CP*GP*TP*TP*TP*TP*GP*TP*GP*G)-3') | dna | 11 | — | — |
| B | Actinomycin D | protein | 10 | 0% helix, 20% strand | — |
Ligands and binding sites
- PXZ · 2-amino-1,9-dicarbonyl-4,6-dimethyl-10-dehydro-phenoxazin-3-one · ligand · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- A–B · 458 Ų buried · 5 hydrogen bonds · protein-nucleic
Modifications
Observed in the structure: 4 modified, 2 covalent, 2 d-amino (methylation, covalent ligand, D-amino acid).
Compared structures
- 1OVF · NMR Structure of ActD/5'-CCGTTTTGTGG-3' Complex · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 1OVF · PDBe 1OVF
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