MolNFT v1 · #174819 · protein
Crystal structures of AKR1C3 ternary complex with NADP+ and the chromene derivative 2L
7C7H: “Crystal structures of AKR1C3 ternary complex with NADP+ and the chromene derivative 2L”. X-ray diffraction, 2 ligands (NAP, FJU). MolNFT v1 #174819 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7C7H
- Type
- protein
- Length
- 634 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P42330
- Ligands
- NAP, FJU
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 316 | — | P42330 |
| B | — | protein | 318 | — | P42330 |
Ligands and binding sites
- NAP · Nadp nicotinamide-adenine-dinucleotide phosphate · ligand · 2 copies · chains A, B
- FJU · 2-azanylidene-N-(3-ethylphenyl)-8-oxidanyl-chromene-3-carboxamide · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7C7H · Crystal structures of AKR1C3 ternary complex with NADP+ and the chromene derivative 2l · the same entry in another collection · chain A against A, TM-score 1.00
- P42330 · AlphaFold monomer V2.0 prediction for aldo-keto reductase family 1 member C3 (P42330) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P42330
- Elsewhere: RCSB PDB 7C7H · PDBe 7C7H · UniProt P42330
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