MolNFT v1 · #174793 · protein

Crystal structure of beta-glycosides-binding protein (W177X) of ABC transporter in a closed state bound to cellopentaose

7C6R · Sugar ABC transporter, periplasmic sugar-binding protein: “Crystal structure of beta-glycosides-binding protein (W177X) of ABC transporter in a closed state bound to…”. X-ray diffraction, 3 ligands (BGC, CL, SO4), 2 pockets (best…

PDB: 7C6R
Type: protein
Length: 414 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Sugar ABC transporter, periplasmic sugar-binding protein
UniProt: Q53W80
Ligands: BGC, CL, SO4
Pockets: 2 · best druggability 0.75

Structure

x-ray diffraction · 1 distinct chain · 49% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Sugar ABC transporter, periplasmic sugar-binding protein	protein	414	49% helix, 15% strand	Q53W80

Ligands and binding sites

BGC · beta-D-glucopyranose · sugar · 5 copies · chains A
CL · Chloride ion · ion · chains A
SO4 · Sulfate ion · ion · chains A
EDO · 1,2-ethanediol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	556	0.75	0.82	64	BGC, CL, EDO
2	54	0.33	0.77	14	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

7C6R · Crystal structure of beta-glycosides-binding protein (W177X) of ABC transporter in a… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q53W80
Elsewhere: RCSB PDB 7C6R · PDBe 7C6R · UniProt Q53W80

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.