MolNFT v1 · #174781 · protein
Crystal structure of beta-glycosides-binding protein (W177X) of ABC transporter in an open state
7C6F · Sugar ABC transporter, periplasmic sugar-binding protein: “Crystal structure of beta-glycosides-binding protein (W177X) of ABC transporter in an open state”. X-ray diffraction, 2 ligands (CL, SO3), 1 pocket (best druggability 0.71).…
- PDB
- 7C6F
- Type
- protein
- Length
- 416 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Sugar ABC transporter, periplasmic sugar-binding protein
- UniProt
- Q53W80
- Ligands
- CL, SO3
- Pockets
- 1 · best druggability 0.71
Structure
x-ray diffraction · 1 distinct chain · 50% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sugar ABC transporter, periplasmic sugar-binding protein | protein | 416 | 50% helix, 16% strand | Q53W80 |
Ligands and binding sites
- CL · Chloride ion · ion · 4 copies · chains A
- SO3 · Sulfite ion · ion · 2 copies · chains A
- EDO · 1,2-ethanediol · additive · 2 copies · chains A
- ACT · Acetate ion · additive · chains A
- PGE · Triethylene glycol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 619 | 0.71 | 0.78 | 70 | CL, PGE |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 7C6F · Crystal structure of beta-glycosides-binding protein (W177X) of ABC transporter in an… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q53W80
- Elsewhere: RCSB PDB 7C6F · PDBe 7C6F · UniProt Q53W80
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